LONGEVITY AT LOWESTOFT.

Bifenthrin longevity at the termiticidal application rate.

BACKGROUND The longevity, mobility and insecticidal activity of bifenthrin at the termiticidal application rate for perimeter treatment were investigated in packed-soil columns in the laboratory and greenhouse. RESULTS Bifenthrin was not detected in the eluates of packed-soil cones over a period of 6 months. In larger pipe plots incorporating bifenthrin into the top 15 cm of the soil, the com...

Familial Longevity Is Marked by Better Cognitive Performance at Middle Age: The Leiden Longevity Study

BACKGROUND Decline in cognitive performance is a highly prevalent health condition in elderly. We studied whether offspring of nonagenarian siblings with a familial history of longevity, perform better on cognitive tests compared to their partners as controls. This is relevant since it could provide insights into determinants underlying decline in cognitive performance. METHODS Cross-sectiona...

Handgrip strength at midlife and familial longevity The Leiden Longevity Study

Low handgrip strength has been linked with premature mortality in diverse samples of middle-aged and elderly subjects. The value of handgrip strength as marker of “exceptional” human longevity has not been previously explored. We postulated that the genetic influence on extreme survival might also be involved in the muscular strength determination pathway. Therefore, the objective of this study...

Human insulin/IGF-1 and familial longevity at middle age

Recently, we have shown that compared to controls, long-lived familial nonagenarians (mean age: 93.4 years) from the Leiden Longevity Study displayed a lower mortality rate, and their middle-aged offspring displayed a lower prevalence of cardio-metabolic diseases, including diabetes mellitus. The evolutionarily conserved insulin/IGF-1 signaling (IIS) pathway has been implicated in longevity in ...

Cross-organelle communication at the core of longevity